Ligand creation via linking—a rapid and convenient method for construction of novel supported PyOX-ligands |
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| Authors: | Markku J. Oila |
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| Affiliation: | Laboratory of Organic Chemistry, Helsinki University of Technology, PO Box 6100, FIN-02015 HUT Espoo, Finland |
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| Abstract: | ![]()
A novel supported amino alcohol linker was synthesized and utilized for attachment of picolinic acid derivatives onto different supports. When the resin bound molecule was further activated, the PyOX-moiety could be constructed reliably in enantiopure form. Furthermore, an efficient Pd-catalyzed modification of a picolinic acid derivative is presented. |
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| Keywords: | Supported PyOX-ligand Amino alcohol linker Tyrosine Picolinic acid derivative |
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