Stereospecific and Stereoselective Rhodium(I)‐Catalyzed Intramolecular [2+2+2] Cycloaddition of Allene‐Ene‐Ynes: Construction of Bicyclo[4.1.0]heptenes |
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| Authors: | Yuu Ohta Dr. Shigeo Yasuda Yuka Yokogawa Kei Kurokawa Prof. Dr. Chisato Mukai |
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| Affiliation: | Division of Pharmaceutical Sciences, Graduate School of Medical Sciences, Kanazawa University, Kakuma‐machi, Kanazawa 920‐1192 (Japan) |
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| Abstract: | Treatment of the allene‐ene‐yne substrates with [{RhCl(CO)2}2] effected the intramolecular [2+2+2]‐type ring‐closing reaction to produce various of tri‐ and tetracyclic derivatives containing a cyclopropane ring. The reaction is highly stereoselective as well as stereospecific with good to excellent yields. |
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| Keywords: | alkynes allenes cycloadditions diastereoselectivity rhodium |
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