首页 | 本学科首页   官方微博 | 高级检索  
     


Synthesis of 3H[1,2]diazepino[5,6-b]indole and 3H[1,2]diazepino[4,5-b]indole derivatives
Authors:A. Monge  J. A. Palop  T. Goñi  A. Martinez  E. Fernández-Alvarez
Affiliation:1. Facultad de Farmacia, Departamento de Química Orgánica y Farmaceutica, Universidad de Navarra, Pamplona, Spain;2. Centro Nacional de Química Orgánica, C/Juan de la Cierva, No. 3, Madrid-6, Spain
Abstract:
The synthesis of two new derivatives of 3H[1,2]diazepino[5,6-b]indole, 5 and 11 , and one new derivative of 3H[1,2]diazepino[4,5-b]indole, 16 , are described. Compound 5 was obtained by the reaction of methyl 2-(3-methoxycarbonyl-1-methylindole)acetate 2 , with hydrazine. Compound 11 was obtained in two ways from ethyl 2-(1-methylindole)acetate ( 8 ) by formylation and reaction with hydrazine. Compound 16 was obtained treating 3-(2-ethoxycarbonylindole)acetonitrile ( 14 ) with hydrazine.
Keywords:
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号