结合光学成像技术研究单颗粒碰撞电化学

近年来，单颗粒碰撞技术在纳米电化学领域受到广泛关注. 该技术通常控制超微电极处于某一电位，检测单个纳米颗粒随机碰撞到电极表面后产生的瞬时电流. 通过分析电流信号，可以研究单个纳米颗粒的性质. 尽管该技术可以检测单个纳米颗粒的电化学或电催化电流，但是传统的单颗粒碰撞技术缺乏空间分辨率，难以识别和表征特定的纳米颗粒. 因此，结合光学成像技术研究单颗粒碰撞电化学来补充电化学技术缺失的空间信息已成为一种趋势. 本文首先简要综述了单颗粒碰撞技术的三种检测原理，主要介绍了近年来单颗粒碰撞技术与荧光显微镜、表面等离激元共振显微镜、全息显微镜和电致化学发光相结合的研究进展，最后展望了单颗粒碰撞技术未来的发展趋势.

Correlated Optical Imaging and Electrochemical Recording for Studying Single Nanoparticle Collisions

With the development of nano-fabrications in recent years, a novel strategy based on random collisions of single electroactive nanoparticles (NPs) onto an inert ultramicroelectrode (UME) has been emerged in the field of nanoelectrochemistry, and named as single nanoparticles collisions (SNCs). The technique uses a chronoamperometric method to detect transient current generated by random collisions of single NPs onto an UME. By analyzing the current signal, one could study the properties of single NPs. Although this technique can detect electrochemical or electrocatalytic currents of a single NP, the traditional SNCs technology lacks necessary spatial resolution to identify and characterize a specific NP. Therefore, several optical imaging techniques have been combined with SNCs strategy to provide spatial information together with electrochemical currents. In this review, we summarize three detection principles of SNCs and provide a brief overview in the combination of SNCs with several optical imaging techniques. We finally conclude with the future trends in developments of SNCs.