| 分子印迹水相分离技术及其在分析化学中的应用 |
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| 引用本文： | 张慧,何华,李洁,李卉,姚誉阳.分子印迹水相分离技术及其在分析化学中的应用[J].化学进展,2011(10):2140-2150. |
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| 作者姓名： | 张慧 何华 李洁 李卉 姚誉阳 |
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| 作者单位： | 中国药科大学分析化学教研室;药物质量与安全预警教育部重点实验室; |
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| 基金项目： | “新药创制”重大专项(No.2009ZX09301-006); 中央高校基本科研业务费专项资金(No.JKY2009059); 浙江省自然科学基金项目(No.Y4110235)资助 |
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| 摘 要： | 分子印迹分离技术通过模拟抗体-抗原相互作用原理,专一地与目标分子互补性结合,从而将目标分子与杂质分离,是一种非常具有发展前景的分离技术。传统的分子印迹技术通常是在有机相中制备对印迹分子具有选择性的印迹聚合物,然而分子印迹技术的实际应用环境大多是水相体系。近年来,分子印迹水相分离技术受到了科学工作者的广泛关注。本文分别从...
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| 关 键 词： | 分子印迹技术 水相分离 分子印迹聚合物 |
Water-Compatible Molecular Imprinting Separation Technique and Its Application in Analytical Chemistry |
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| Zhang Hui He Hua, Li Jie Li Hui Yao Yuyang.Water-Compatible Molecular Imprinting Separation Technique and Its Application in Analytical Chemistry[J].Progress in Chemistry,2011(10):2140-2150. |
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| Authors: | Zhang Hui He Hua Li Jie Li Hui Yao Yuyang |
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| Institution: | Zhang Hui1 He Hua1,2 Li Jie1 Li Hui1 Yao Yuyang1(1.Department of Analytical Chemistry,China Pharmaceutical University,Nanjing 210009,China,2.Key Laboratory of Drug Quality Control and Pharmacovigilance,Ministry of Education,China) |
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| Abstract: | Molecular imprinting separation technique can effectively separate the target molecules from impurities by specially binding the target molecules based on imitating the way of interaction between antigen and antibody.It is a very promising separation technique.In the traditional molecular imprinting techniques,imprinted polymers are usually prepared for selectively adsorbing the template molecule in organic solvents.However,most of the practical applications of molecular imprinting technique are in aqueous ... |
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| Keywords: | molecular imprinting technique water-phase separation molecularly imprinted polymers(MIP) |
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