Synthesis and spectral properties of substituted 4-chlorooxazoloquinolines

Summary The treatment of a mixture of linearly and angularly annelated 2-substituted oxazolo4,5-f]quinolones (5a–c) and oxazolo5,4-g]quinolones (6a–c) and similarly the treatment of 2-substituted oxazolo5,4-f]quinolones (7a–c) and oxazolo4,5-g]quinolones (8b,c) with POCl₃ afforded substituted 4-chlorooxazolo4,5-f]quinolines (9a–c) and 2-substituted 4-chlorooxazolo5,4-f]quinolines (10b,c), respectively. Spectral characteristics of the synthesized derivatives (¹H and¹³C NMR, IR, UV, and MS) are discussed.Dedicated to Prof.Fritz Sauter on the occasion of his 65th birthday