Basic calculations about the limit of detection and its optimal determination |
| |
| Authors: | Email author" target="_blank">Walter?HuberEmail author |
| |
| Institution: | (1) Laboratoire d'Informatique pour la Mécanique et les Sciences de l'Ingénieur, LIMSI-CNRS (UPR3251), BP 133, 91403 Orsay CEDEX Orsay, France;(2) Laboratoire d'Aérothermique, CNRS UPR 9020, 1C avenue de la Recherche Scientifique, 45067 Orléans Cedex 2 Orléans , France;(3) Laboratoire de Mécanique Théorique et Appliquée, CNRS UMR 7563, 2 avenue de la Forêt de Haye, 54516 Vandoeuvre lès Nancy, France |
| |
| Abstract: | The limit of detection (LOD) is based strictly on an accepted probability for a false positive decision (type 1 error). For the needed standard deviation of the blank, a basic value for the calculation, three experimental different methods are described, which should be applicable in every case. Table values for simple but exact calculation, not only for single, but also for mean values, and with probabilities for the type 1 error of 1% and 5% are presented. Demands for an acceptable uncertainty of the LOD and for the validation of the result are specified. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
