A Fluorescence Optical Fiber Sensor for Amrinon Using a New Oxazole Compound

Anew oxazole compound, 1,4-bis(naphtho[1,2-d][1,3]oxazol-2-yl)benzene(BNOB) was synthesized and incorporated into a thin plasticized polymeric membrane for sensing Amrinon. The sensor exhibits a linear response to Amrinon in the range of 7.98×10^-7-1.52×10^-4 mol/L at pH 3. 28-4.04. The response mainly originates from the Primary Inner Filter Effect, which causes a decrease in the fluorescence intensity of the sensor membrane. The distinct advantages of the proposed sensor are of full reversibility, high sensitivity and selectivity as well as short response time(<1 min), indicating that the sensor can be used to monitor Amrinon in serum samples.