| 主链含酪氨酸聚磷酸酯药物控制释放材料的研究 |
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| 引用本文： | 范昌烈,胡斌,卓仁禧.主链含酪氨酸聚磷酸酯药物控制释放材料的研究[J].高等学校化学学报,1995,16(11):1802. |
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| 作者姓名： | 范昌烈 胡斌 卓仁禧 |
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| 作者单位： | 武汉大学化学系, 武汉, 430072 |
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| 摘 要： | 采用溶液缩聚方法制备了含酪氨酸烷基酯的聚磷酸酯,研究了聚合物对氨甲蝶呤的体外释放性能和聚合物包裹氨甲蝶呤微胶囊的制备方法及其释药性能
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| 关 键 词： | 聚磷酸酯 药物控制释放材料 酪氨酸 氨甲蝶呤 微胶囊 |
| 收稿时间： | 1994-11-10 |
Studies on the Drug Controlled Release Materials of Polyphosphate Containing Tyrosine Ester |
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| FAN Chang-Lie,HU Bin,ZHUO Ren-Xi.Studies on the Drug Controlled Release Materials of Polyphosphate Containing Tyrosine Ester[J].Chemical Research In Chinese Universities,1995,16(11):1802. |
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| Authors: | FAN Chang-Lie HU Bin ZHUO Ren-Xi |
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| Institution: | Department of Chemistry, Wuhan University, Wuhan, 430072 |
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| Abstract: | Novel polyphosphates containing tyrosine alkyl ester were synthesized by solutionpolycondensation in the presence of catalytic amount of DMAP. The release properties ofmethotrexate(MXT)from these polyphosphates and their microcapsules including MTX were studied. |
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| Keywords: | Polyphosphate Drug controlled release materials L-Tyrosine Methotrexate(MTX) Microcapsule |
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