Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part II: Five-Membered Aromatic Rings with Multi Heteroatoms |
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Authors: | Eslam Reda El-Sawy Ahmed Bakr Abdelwahab Gilbert Kirsch |
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Institution: | 1.National Research Centre, Chemistry of Natural Compounds Department, Dokki, Cairo 12622, Egypt;2.Plant Advanced Technologies (PAT), 54500 Vandoeuvre-les-Nancy, France;3.Laboratoire Lorrain de Chimie Moléculaire (L.2.C.M.), Université de Lorraine, 57078 Metz, France |
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Abstract: | Coumarins are natural heterocycles that widely contribute to the design of various biologically active compounds. Fusing different aromatic heterocycles with coumarin at its 3,4-position is one of the interesting approaches to generating novel molecules with various biological activities. During our continuing interest in assembling information about fused five-membered aromatic heterocycles, and after having presented mono-hetero-atomic five-membered aromatic heterocycles in Part I. The current review Part II is intended to present an overview of the different synthetic routes to coumarin (benzopyrone)-fused five-membered aromatic heterocycles with multi-heteroatoms built on the pyrone ring, covering the literature from 1945 to 2021. |
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Keywords: | coumarins benzopyrones pyrazole imidazole thiazole oxazole triazole thiadiazole |
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