| Abstract: | Five novel triorganotin(Ⅳ) complexes have been synthesized by refluxing trimethyl, triethyl, tributyl, triphenyl and tribenzyltin chloride with Cephlaxine.These compounds were characterized by spectroscopic (IR,1H, 13C, 119Sn NMR) techniques and elemental analysis.The results obtained through these techniques are in full agreement with the proposed 1:1 stoichiometry.The synthesized compounds were than tested against various microorganisms and fungi.The results of new products obtained showed that the triphenyltin(IV) complex displayed promising activity against all types of bacteria and fungi used while all other compounds showed significant antibacterial and antifungal activity. |
