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Analogs of pyrimidine nucleosides
Authors:D Ya Sniker  R A Zhuk  E I Stankevich  G Ya Dubur  S A Hiller
Institution:(1) Institute of Organic Synthesis AS LatvSSR, Riga
Abstract:The reaction of alkoxy bromides with N1-(agr-tetrahydrofuryl) derivatives of pyrimidine bases has given a series of 6-alkoxy-5-bromo-1-(agr-tetrahydrofuryl)-5, 6-dihydrouracils. The hydrogenation of the 1-(agr-tetrahydrofuryl) derivatives of uracil and of 5-fluorouracil has been studied. It has been shown that in both cases 1-(agr-tetrahydrofuryl)-5, 6-dihydrouracil is formed.
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