Analogs of pyrimidine nucleosides |
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Authors: | D Ya Sniker R A Zhuk E I Stankevich G Ya Dubur S A Hiller |
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Institution: | (1) Institute of Organic Synthesis AS LatvSSR, Riga |
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Abstract: | The reaction of alkoxy bromides with N1-(-tetrahydrofuryl) derivatives of pyrimidine bases has given a series of 6-alkoxy-5-bromo-1-(-tetrahydrofuryl)-5, 6-dihydrouracils. The hydrogenation of the 1-(-tetrahydrofuryl) derivatives of uracil and of 5-fluorouracil has been studied. It has been shown that in both cases 1-(-tetrahydrofuryl)-5, 6-dihydrouracil is formed. |
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