生物样品中神经递质的定量测定及其应用研究进展

神经递质(NTs)是神经传递的内源性化学信使,在大脑功能中发挥重要作用。中枢神经系统中神经递质浓度的变化与许多精神和生理疾病有关。神经递质的测定已成为疾病诊断和监测以及治疗干预的重要手段,有效的神经递质体内监测对于疾病诊疗乃至新药研发都至关重要。该文就近年来神经递质的检测方法,包括仪器检测法、电化学检测法以及一些新型检测方法等进行综述,并总结了目前神经递质检测在一些疾病研究中的应用进展。

Research advancement in the determination of neurotransmitters in biological samples and their applications

Neurotransmitters (NTs) are endogenous chemical messengers that are involved in nerve signal transmission and play important roles in brain function. Changes in NT concentrations in the central nervous system are related to many mental and physiological illnesses. The determination of various NTs has become important in disease diagnosis, monitoring, and treatment interventions. Effective monitoring of NTs in vivo is essential for disease diagnosis and treatment as well as for the research and development of new drugs. This article provides a review of the methods used in NT detection in recent years, including instrumental and electrochemical techniques as well as some new detection methods, and summarizes the applications of the methods for NT detection in some diseases.