Development of an access route to the c31-c52 central core of amphidinol 3 |
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Authors: | Bedore Matthew W Chang Shuh-Kuen Paquette Leo A |
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Affiliation: | Evans Chemical Laboratories, The Ohio State University, Columbus, Ohio 43210, USA. |
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Abstract: | [reaction: see text] An asymmetric synthesis of the heavily oxygenated inner sector of amphidinol 3 constituted of C31-C52 is described. The successful pathway highlights construction of the pair of identical tetrahydropyran subunits from a common intermediate. |
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