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ent‐Kaurane Diterpenes and Further Constituents from Wedelia trilobata
Authors:Yin Qiang  Dao‐Lin Du  Yan‐Jun Chen  Kun Gao
Institution:1. State Key Laboratory of Applied Organic Chemistry and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P.?R. China, (phone: +86‐931‐8912592;2. fax: +86‐931‐8912582);3. School of Environment, Jiangsu University, Zhenjiang 212013, P.?R. China;4. School of Biotechnology and Chemical Engineering, Ningbo Institute of Technology, Zhejiang University, Ningbo 315100, P.?R. China
Abstract:Two new ent‐kaurane diterpenes, wedelidins A ( 8 ) and B ( 9 ), together with eighteen other constituents, including the sesquiterpenoids 1 and 2 , ent‐kaurane diterpenes 3 – 7 , triterpenoids 10 and 11 , steroids 12 – 14 , and flavonoids 15 – 17 as well as benzene derivatives 18 – 20 , were isolated from the aerial parts of Wedelia trilobata. The structures of wedelidins A ( 8 ) and B ( 9 ) were elucidated by extensive spectroscopic analyses (including UV, IR, NMR, and MS). Furthermore, the structures of compounds 2 and 3 were confirmed by X‐ray single‐crystal diffraction analyses.
Keywords:Wedelia trilobata  Diterpenes  Wedelidins A and B  X‐Ray crystallography
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