An Efficient Synthesis of [(Tosylamino)alkyl]naphthalenols by Nucleophilic Addition of Naphthalen‐2‐ol with N‐Tosyl Imines Using Boron Trifluoride Etherate as Catalyst |
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| Authors: | Biswanath Das Cheruku Ravindra Reddy Chava Sindhu Duddukuri Nandan Kumar Martha Krishnaiah |
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| Affiliation: | 1. Organic Chemistry Division‐I, Indian Institute of Chemical Technology, Hyderabad‐500?007, India, (phone: +91‐40‐7193434;2. fax: +91‐40‐7160512) |
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| Abstract: | [(Tosylamino)alkyl]naphthalenols have efficiently been synthesized by nucleophilic addition of naphthalen‐2‐ol with N‐tosyl imines (derived from both aromatic and aliphatic aldehydes) in the presence of BF3?OEt2 as a catalyst at room temperature. The products are formed within 5–9 h in high yields (72–91%). |
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| Keywords: | Naphthalen‐2‐ols Imines, tosyl‐ Catalysis |
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