Synthesis of Dialkyl 2‐(Alkylamino)‐4,9‐dihydro‐9‐oxocyclohepta[b]pyran‐3,4‐dicarboxylates |
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| Authors: | Javad Azizian Ali Ramazani Mohammad Haji |
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| Institution: | 1. Chemistry Department, Science and Research Branch, Islamic Azad University, P.O. Box 19395‐1775, Tehran, Iran;2. Chemistry Department, Islamic Azad University, Zanjan Branch, P.O. Box 45195‐467, Zanjan, Iran, (fax: +98?241?4213955) |
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| Abstract: | Dialkyl 2‐(alkylamino)‐4,9‐dihydro‐9‐oxocycloheptab]pyran‐3,4‐dicarboxylates are prepared in a one‐pot three‐component reaction of alkyl isocyanide, dialkyl acetylenedicarboxylate, and α‐tropolone (=2‐hydroxycyclohepta‐2,4,6‐trienone). The reaction proceeds smoothly at room temperature and under neutral conditions to afford tropolone derivatives in high yield. |
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| Keywords: | α ‐Tropolone Acetylenedicarboxylate dialkyl Multicomponent reactions Isocyanide alkyl Cyclohepta[b]pyran‐3 4‐dicarboxylates |
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