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Cover Picture: Studies of Glutathione Transferase P1‐1 Bound to a Platinum(IV)‐Based Anticancer Compound Reveal the Molecular Basis of Its Activation (Chem. Eur. J. 28/2011)
Authors:Lorien J Parker  Louis C Italiano  Craig J Morton  Nancy C Hancock  David B Ascher  Jade B Aitken  Hugh H Harris  Pablo Campomanes  Ursula Rothlisberger  Anastasia De Luca  Mario Lo Bello  Wee Han Ang  Paul J Dyson  Michael W Parker
Institution:1. Biota Structural Biology Laboratory, St. Vincent's Institute of Medical Research, 41 Victoria Parade, Fitzroy, Victoria 3065 (Australia), Fax: (+61)?3‐9416‐2676;2. Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, 30 Flemington Road, Parkville, Victoria 3010 (Australia);3. School of Chemistry, The University of Sydney, New South Wales 2006 (Australia);4. School of Chemistry and Physics, University of Adelaide, South Australia 5005 (Australia);5. Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne (Switzerland);6. Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica 1, Rome 00133 (Italy);7. Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543 (Singapore)
Abstract:
Keywords:antitumor agents  detoxification  ethacrynic acid  glutathione transferases  X‐ray crystallography
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