Application of self-assembly techniques in the design of biocompatible protein microarray surfaces |
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Authors: | Schaeferling Michael Schiller Stefan Paul Hubert Kruschina Margit Pavlickova Petra Meerkamp Mark Giammasi Chiara Kambhampati Dev |
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Affiliation: | University of Regensburg, Institute of Analytical Chemistry, Chemo- and Biosensors, Regensburg, Germany. |
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Abstract: | ![]() This review focuses on the application of novel technologies for generating biocompatible surfaces for high-throughput screening (HTS) of proteins. Various methods of coupling and spotting proteins on self-assembled monolayer (SAM) surfaces will be described along with the protein chip challenges pertaining to spot homogeneity, morphology, biocompatibility and reproducibility. |
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