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Application of self-assembly techniques in the design of biocompatible protein microarray surfaces
Authors:Schaeferling Michael  Schiller Stefan  Paul Hubert  Kruschina Margit  Pavlickova Petra  Meerkamp Mark  Giammasi Chiara  Kambhampati Dev
Affiliation:University of Regensburg, Institute of Analytical Chemistry, Chemo- and Biosensors, Regensburg, Germany.
Abstract:
This review focuses on the application of novel technologies for generating biocompatible surfaces for high-throughput screening (HTS) of proteins. Various methods of coupling and spotting proteins on self-assembled monolayer (SAM) surfaces will be described along with the protein chip challenges pertaining to spot homogeneity, morphology, biocompatibility and reproducibility.
Keywords:
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