A homogenization approach to flashing ratchets

The paper continues the program of the authors to develop a mathematical framework to understand and characterize the notion of “asymmetric” potentials, which has been introduced to explain how molecular motors work, considering flashing ratchets, i.e., molecules diffusing in a potential with periodic switches. The mathematical model is a Fokker–Planck equation with a space–time periodic potential and diffusion of order of magnitude compatible with the period of the potential. After performing a homogenization analysis of the problem the “asymmetric” potentials are characterized by the property that the solution, which models the molecule density, concentrates on one end of the domain. Finally explicit examples are presented exhibiting that the concentration phenomena (motor effect) takes place are presented. The proof uses techniques from the theory of viscosity solutions for the Hamilton–Jacobi equation which, in the homogenization limit, defines the effective hamiltonian.