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Convenient Preparation of α-Tert-Butyl N-Blocked Glutamates Through γ-Allyl Ester Protection |
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| Authors: | V Bavetsias G M F Bisset M Jarman |
| Institution: | CRC Centre for Cancer Therapeutics at the Institute of Cancer Research, Chemistry Department, CRC Laboratories , 15 Cotswold Road Sutton, Surrey, SM2 5NG, England |
| Abstract: | Utilisation of γ-allyl ester protection of glutamates provides a convenient route to the synthesis of Z-Glu-OBut, Tr-Glu-OBut and (Boc)2-Glu-OBut. |
| Keywords: | Thieno‐[3 2‐c]‐quinolone 1‐alkyl‐4‐mercaptoquinoline‐2(1H)‐one thio‐Claisen rearrangement regioselective synthesis sulfur heterocycles |