Synthesis of Isobrassilexin,a Biologically Active Isomer of Brassilexin,a Cruciferac Phytoalexin |
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| Authors: | Michel Barbier Michel Devys Christiane Tempěte Albert Kollmann Jean-Francois Bousquet |
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| Institution: | 1. Institut de Chimie des Substances Naturelles , CNRS, Avenue de la Terrasse, 91198, Gif sur Yvette, Cedex, France;2. Station Centrale de Pathologie Végétale, CNRA , 78000, Versailles, France |
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| Abstract: | The synthesis of isobrassilexin 2, a hitherto non natural indoloisothiazole is reported (two steps, 43% yield). This substance, an isomer of brassilexin 1 has shown important biological properties in vitro. |
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