A Mild Method for the Esterification of Fatty Acids |
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| Authors: | Frederick E. Ziegler Gregory D. Berger |
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| Affiliation: | Sterling Chemistry Laboratory Yale University , New Haven, CT, 06520 |
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| Abstract: | ![]()
In conjunction with a synthetic problem, we were in need of a method for the stoichiometric esterification of fatty acids, containing the aqueous acid labile tert-butyl dimethylsilyloxy group (OTBS), with a variety of alcohols. It has been reported2 that fatty acids form acylureas in the presence of dicyclo-hexylcarbodiimide (DCC) and methanol3 without esterification. |
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