Asymmetric Syntheses IV: Enantioselective Synthesis of (R)-Benzylic Amines Via Alkylation of D-Camphor Ketimine |
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| Authors: | Jiang Yaozhong Liu Guilan Liu Jinchu Zhou Changyou Chengdu |
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| Institution: | Institute of Organic Chemistry, Academia Sinica , Chengdu, P.R. China |
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| Abstract: | An efficient asymmetric synthesis of (R)-benzylic amines in optical purity 36–90% had been achieved by alkylation of a chiral ketimine prepared from D-camphor and benzylamine. Diastereoselectivity in the alkylation is dependent on the alkyl halides. |
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