Selective Deprotection Of tert-Butyldimethylsilyl Ether With Lithium Bromide And 18-Crown-6 |
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| Authors: | Manish Tandon Tadhg P. Begley |
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| Affiliation: | Department of Chemistry , Cornell University , Ithaca, New York, 14853, U.S.A. |
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| Abstract: | ![]()
Lithium bromide, in the presence of a crown ether, has been found to selectively remove primary tert-butyldimethylsilyl ethers under controlled conditions. This selectivity has been utilized to synthesize 3′-TBDMS-2′-deoxyuridine in one step from the diprotected compound. |
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| Keywords: | Hydroformylation Catalysis Aldol condensation Allylpyrroles Indolizines |
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