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Palladium‐catalyzed cyclization of 3‐bromopyridine‐4‐carbaldehyde with carbon monoxide and carboxylic acids
Authors:Chan Sik Cho  Jun Uk Kim
Abstract: chemical structure image 3‐Bromopyridine‐4‐carbaldehyde is cyclized with carboxylic acids in acetonitrile at 100° under carbon monoxide pressure in the presence of a catalytic amount of a palladium catalyst along with a base to afford the corresponding 3‐oxo‐1,3‐dihydrofuro3,4‐c]pyridine‐1‐yl alkanoates in moderate to good yields.
Keywords:
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