Synthesis of 4-(2-chloroethyl)-2,3-dihydro[1,4]oxazino[2,3-b]quinoline and 4-(2-chloroethyl)2,3-dihydropyrido[2,3-b][1,4]oxazine |
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Authors: | Wayne K Anderson Deepak K Dalvie |
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Abstract: | The title compounds were synthesized from 3-bis(2-hydroxyethyl)amino]quinolin-2(1H)-one 11a and 3-bis(2-hydroxyethyl)amino]pyridin-2(1H)-one 18 respectively. The preparation involved a tandem chlorination/cyclization reaction. |
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