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A convenient synthesis of cis-4-(sulfomethyl)-piperidine-2-carboxylic acid: NMR assignment |
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| Authors: | Ahmed El Hadri,G Rard Leclerc |
| Affiliation: | Ahmed El Hadri,GÉRard Leclerc |
| Abstract: | cis-4-(Sulfomethyl)piperidine-2-carboxylic acid was obtained in 22% overall yield from 4-(hydroxymethyl)-pyridine via the o-silyl N-oxide and trimethylsilylcyanide. The cis configuration of 5 was unambiguously assigned by 200 MHz 1H nmr and cosy experiments. |
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