Spectral,Thermal, and Antimicrobial Studies on the Copper(II), Zinc(II), Cadmium(II), and Mercury(II) Chelates of a New Antimetabolite–5-Dimethylaminomethyl-2-Thiouracil

Owing to the presence of multiple donor atoms such as N(1)H, C(2)SH, N(3), C(4)O, and CNC in the newly synthesized antimetabolite, namely, 5-dimethylaminomethyl-2-thiouracil, preferences of the hetero-atoms for coordination with metal ions like Cu(II), Zn(II), Cd(II), and Hg(II) were explored. The complexes isolated were characterized by chemical analysis and spectroscopic techniques. The ligand behaves as a bidentate/tetradentate chelating ligand. Invariably in all the complexes, one of the donor atoms is the soft C(2)SH. The kinetic and thermodynamic parameters for the thermal decomposition of the metal chelates were evaluated using (Coats–Redfern) and (Madhusudanan–Krishnan–Ninan) equations. The antimicrobial studies show that the copper(II) complexes are more active than the other complexes.