Synthesis and Crystal Structure of Copper(II) Complex with N-Acetoxyl-picolinamide

1 INTRODUCTION The picoloylhydrazide compounds are close to thebiologic environment and can react with microele-ments in organism so as to have antitubercular andantineoplastic activities. However, owing to the exis-tence of amino group, this kind of compounds aretoxic to some extent[1]. In order to decrease theirtoxicity, hydrazone or hydrazide compounds synthe-sized by the condensation reaction of amino and car-bonyl groups have been well studied in recentyears[1～7]. Herein we report t…

Synthesis and Crystal Structure of Copper(II) Complex with N-Acetoxyl-picolinamide

Using Cu(II) as the template, a complex {[Cu2L2(H2O)2]·4H2O}n (L = N-acetoxyl- picolinamide) has been successfully synthesized and characterized by single-crystal X-ray diffrac- tion. The crystal is of monoclinic, space group C2/c, with a = 24.144(5), b = 7.1622(14), c = 17.283(4) ?, C16H24Cu2N4O12, Mr = 591.47, β = 131.73(3)o, V = 2230.3(8) ?3, Z = 4, Dc = 1.761 g/cm3, F(000) = 1208, μ = 1.978 mm?1, R = 0.0400 and wR = 0.1099. The copper (II) ion is five- coordinated with a distorted square pyramidal geometry. The complex can be viewed as a one- dimensional chain structure by carboxylic bridges among copper atoms. In the complex there exist hydrogen bonding interactions to stabilize the structure.