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Synthesis,structure elucidation and plants growth promoting effects of novel quinolinyl chalcones
Institution:1. Chemistry Department, Faculty of Education, Ain Shams University, Roxy, 11711, Cairo, Egypt;2. Biology Department, Faculty of Sciences & Arts (Almikhwah), Al Baha University, Saudi Arabia;3. MSA University, Faculty of Pharmacy, 26 July Mehwer Road Intersection with Wahat Road, 6th October City, Cairo, Egypt
Abstract:The readily synthesized 3-(4-Hydroxy-1-methyl-1,2-dihydro-2-oxoquinolin-3-yl)-1-phenyl-1H-pyrazole-4-carbaldehyd (5) and 3-(2-Oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde (6) were utilized as a convenient starting precursor materials for synthesis of novel enone system 4-hydroxy-1-methyl-3-(4-(2H-2-oxo-chromen-3-yl)prop-2-enoyl)-1-phenyl-1H-pyrazol-4-yl)quinolin-2(1H)-one (7) and4-hydroxy-1-methyl-3-(2E)-3-(3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazol-4-yl)acryloyl)quinolin-2(1H)-one (8). Simple homonuclear NOE experiment (NOESY 1D) method was performed for structure elucidation of the novel quinolinyl chalcones. The synthesized compounds have been estimated for their effect of growth on some selective crop of plants (Hibiscus, Mint and Basil).
Keywords:Pyrazolocarbaldehydes  Chalcones  Homonuclear  Hibiscus  Basil
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