Recent advancement and development of chitin and chitosan-based nanocomposite for drug delivery: Critical approach to clinical research |
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| Affiliation: | 1. Department of Chemistry, The University of Lahore, 54590 Lahore, Pakistan;2. Department of Chemical Engineering, Faculty of Engineering and Science, Curtin University, 98009 Sarawak, Malaysia;3. Department of Chemistry, Faculty of Sciences, University of Central Punjab, Lahore 54000, Pakistan;4. Department of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan;5. Department of Environmental Science and Engineering, Government College University, Faisalabad 38000, Pakistan;6. Laboratory of Quality of Vegetables and Medicinal Plants, Department of Vegetable Crops and Medicinal Plants, University of Life Sciences in Lublin, 15 Akademicka Street, 20-950 Lublin, Poland;7. School of Electrical and Information Engineering, Tianjin University, 92 Weijin Road, Nankai District, Tianjin 300072, China;8. Biology Department, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia;9. Department of Zoology, Science College, King Saud University, Riyadh 11451, Saudi Arabia;10. Department of Environmental Science, The University of Lahore, Lahore 54590, Pakistan;11. Department of Earth Sciences, University of Sargodha, 40100 Sargodha, Pakistan;12. Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt;13. Department of Biological Sciences and Technology, China Medical University (CMU), Taiwan;14. School of Materials Science and Engineering, Jiangsu University, Zhenjiang 212013, China |
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| Abstract: | This review depicts the exposure of chitin and chitosan base multifunctional nanomaterial composites for promising applications in field of biomedical science structure, synthesis as well as potential application from a colossal angle. We elaborated critically each of the chitin and chitosan base nanomaterial with its potential application toward biomedical science. For different biomedical applications it use in form of hydrogels, microsphere, nanoparticles, aerogels, microsphere and in form of scaffold. Due to this it had been blended with different polymer such as starch, cellulose, alginate, lipid, hyaluronic acid, polyvinyl alcohol and caboxymethyl cellulose. In this review article, a comprehensive overview of combination of chitin and chitosan base nanomaterial with natural as well as synthetic polymers and their biomedical applications in biomedical field involving drug delivery system all the technical scientific issues have been addressed; highlighting the recent advancements. |
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| Keywords: | Chitin Chitosan Natural polymer Nanomaterials Drug delivery Cancer Cur" },{" #name" :" keyword" ," $" :{" id" :" k0040" }," $$" :[{" #name" :" text" ," _" :" Curcumin UV" },{" #name" :" keyword" ," $" :{" id" :" k0050" }," $$" :[{" #name" :" text" ," _" :" Ultraviolet PVA" },{" #name" :" keyword" ," $" :{" id" :" k0060" }," $$" :[{" #name" :" text" ," _" :" Poly vinyl Alcohol LWMG" },{" #name" :" keyword" ," $" :{" id" :" k0070" }," $$" :[{" #name" :" text" ," _" :" low molecular weight gelator HPMC" },{" #name" :" keyword" ," $" :{" id" :" k0080" }," $$" :[{" #name" :" text" ," _" :" Hydroxypropyl methyl cellulose CS" },{" #name" :" keyword" ," $" :{" id" :" k0090" }," $$" :[{" #name" :" text" ," _" :" Chitosan IBM" },{" #name" :" keyword" ," $" :{" id" :" k0100" }," $$" :[{" #name" :" text" ," _" :" Imatinib mesylate CML" },{" #name" :" keyword" ," $" :{" id" :" k0110" }," $$" :[{" #name" :" text" ," _" :" chronic myeloid leukemia DDS" },{" #name" :" keyword" ," $" :{" 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