|
|||||
|
|
A theoretical investigation of chirp insonification of ultrasound contrast agents |
|
| Authors: | Barlow Euan Mulholland Anthony J Gachagan Anthony Nordon Alison |
| Affiliation: | a Department of Mathematics, University of Strathclyde, 26 Richmond Street, Glasgow G1 1XH, UK b Department of Electronic and Electrical Engineering, The Centre for Ultrasonic Engineering (CUE), University of Strathclyde, 204 George Street, Glasgow G1 1XW, UK c WestCHEM, Department of Pure and Applied Chemistry, Centre for Process Analytics and Control Technology (CPACT), University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, UK |
| Abstract: | A theoretical investigation of second harmonic imaging of an Ultrasound Contrast Agent (UCA) under chirp insonification is considered. By solving the UCA’s dynamical equation analytically, the effect that the chirp signal parameters and the UCA shell parameters have on the amplitude of the second harmonic frequency are examined. This allows optimal parameter values to be identified which maximise the UCA’s second harmonic response. A relationship is found for the chirp parameters which ensures that a signal can be designed to resonate a UCA for a given set of shell parameters. It is also shown that the shell thickness, shell viscosity and shell elasticity parameter should be as small as realistically possible in order to maximise the second harmonic amplitude. Keller-Herring, Second Harmonic, Chirp, Ultrasound Contrast Agent. |
| Keywords: | Keller-Herring Second harmonic Chirp Ultrasound contrast agent |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |