Selective Synthesis of Z‐Cinnamyl Ethers and Cinnamyl Alcohols through Visible Light‐Promoted Photocatalytic E to Z Isomerization |
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Authors: | Hengchao Li Hang Chen Yang Zhou Jin Huang Jundan Yi Hongcai Zhao Wei Wang Linhai Jing |
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Abstract: | A photocatalytic E to Z isomerization of alkenes using an iridium photosensitizer under mild reaction conditions is disclosed. This method provides scalable and efficient access to Z‐cinnamyl ether and allylic alcohol derivatives in high yields with excellent stereoselectivity. Importantly, this method also provides a powerful strategy for the selective synthesis of Z‐magnolol and honokiol derivatives possessing potential biological activity. |
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Keywords: | allylic alcohols cinnamyl ethers iridium isomerization photocatalysis |
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