On the synthesis of 3(5)-carbomethoxy-4-hetarylpyrazoles |
| |
| Authors: | Carlos Cativiela Maria D Diaz De Villegas Jos A Mayoral Alberto Avenoza Miguel A Roy |
| |
| Institution: | Carlos Cativiela,Maria D. Diaz De Villegas,José A. Mayoral,Alberto Avenoza,Miguel A. Roy |
| |
| Abstract: | 3(5)-Carbomethoxy-4-hetarylpyrazoles 3 can be obtained by the aromatization of the corresponding cis-3-benzamido-3-carbomethoxy-4-hetaryl-Δ1-pyrazolines 2 obtained by 1,3-dipolar cycloaddition of diazo-methane with methyl Z-2-benzamido-3-hetarylpropenoates 1. An explanation, based on FMO theory, for the different reactivity of the dipolarophiles with diazomethane is given. |
| |
| Keywords: | |
|
|
