Trace analysis of surfactants derived from fatty alcohols I. Optimization of derivatization reaction |
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Authors: | Ch Meissner H Engelhardt |
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Institution: | (1) Institute of Instrumental and Environmental Analysis, University of the Saarland, 66123 Saarbrücken, Germany |
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Abstract: | Summary Pre-column derivatization of the primary hydroxyl group in fatty alcohols and fatty alcohol ethoxylates using carbazole-9-carbonyl
chloride (CC−Cl) and FMOC-Cl is described and compared with derivatization with 1-naphthoyl chloride (N−Cl). As the excess
of derivatization reagent leads to a broad and strongly tailing reagent peak, it hinders trace determination of fatty alcohols
and fatty alcohol ethoxylates. Therefore, an off-line as well as an on-line solid-phase extraction (SPE) method for removal
of excess reagent are described. The on-line method which is based on column switching, shows better reproducibility higher
pre-concentration, lower risk of contamination and can be easily automated, while the off-line method is better suited for
the analysis of derivatized, fatty alcohol ethoxylates. An example of the trace analysis of fatty alcohols with a concentration
of 2 ppb is given. |
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Keywords: | Column liquid chromatograph Column switching Solid phase extraction Derivatization of fatty alcohols FMOC-Cl Carbazole-9-carbonyl chloride |
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