Three-component sequential synthesis of N,N′-disubstituted 5-arylidenedihydropyrimidine-2,4-dione |
| |
| Authors: | Maria Cristina BellucciAlessandro Volonterio |
| |
| Affiliation: | a Dipartimento di Scienze Molecolari Agroalimentari, Università degli Studi di Milano, via Celoria 2, 20133 Milano, Italy
b Department of Chemistry, Materials and Chemical Engineer ‘Giulio Natta’, Politecnico di Milano, via Mancinelli 7, 20131 Milano, Italy |
| |
| Abstract: | A three-component sequential process consisting in (1) in situ formation of carbodiimides by Staudinger reaction, (2) reaction with 2-(bromomethyl)-3-aryl-2-propenoic acids, and (3) final cyclization of the resulting N-acylurea intermediates in order to obtain the synthesis of an array of N,N′-disubstituted 5-arylidenedihydropyrimidine-2,4-dione under mild conditions is presented. |
| |
| Keywords: | Multi-component Sequential synthesis Carbodiimides Dihydropyrimidine-2,4-dione N-Acylurea |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
