Asymmetric synthesis of 1-deoxyazasugars from chiral aziridines |
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| Authors: | Singh Alok Kim Bongchan Lee Won Koo Ha Hyun-Joon |
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| Institution: | Department of Chemistry and Protein Research Centre for Bio-Industry, Hankuk University of Foreign Studies, Yongin, 449-719, Korea. |
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| Abstract: | A general and facile synthesis of enantiopure 1-deoxyazasugars was achieved from stereoselective dihydroxylation of a common synthetic intermediate, piperidine ring fused oxazolidin-2-one, originating from a commercially available starting substrate, chiral aziridine-2-carboxylate, in high yields. |
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