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| The preparation of functionalized single walled carbon nanotubes as high efficiency DNA carriers | |
| 引用本文： | Xiao Ying Yang Zun Feng Liu Jie Mao Shu Jing Wang Yan FengMa Yong Sheng Chen. The preparation of functionalized single walled carbon nanotubes as high efficiency DNA carriers[J]. 中国化学快报, 2007, 18(12): 1551-1553. DOI: 10.1016/j.cclet.2007.10.006 |
| 作者姓名： | Xiao Ying Yang Zun Feng Liu Jie Mao Shu Jing Wang Yan FengMa Yong Sheng Chen |
| 作者单位： | Xiao Ying Yang Zun Feng Liu Jie Mao Shu Jing Wang Yan Feng Ma Yong Sheng Chen ~aSchool of Pharmaceutical Sciences，Tianjin Medical University，Tianjin 300070，China ~bCenter for Nanoscale Science and Technology and Key Laboratory for Functional Polymer Materials，Institute of Polymer Chemistry，Nankai University，Tianjin 300071，China |
| 摘 要： | The positively charged single walled carbon nanotubes (SWNTs~ ) were prepared by conjugating with-CONH-C_6H_(12)-NH_3~ . The double strand DNA(dsDNA) chains were loaded onto SWNTs~ via the electrostatic interactions.SWNTs~ shows improved loading efficiency (353.5μg/mg) toward dsDNA compared with that of charged free single walled carbon nanotubes (SWNTs) (82.9μg/mg). |
| 关 键 词： | 纳米碳管 DNA 化学作用 化学合成 |
| 收稿时间： | 2007-06-26 |
The preparation of functionalized single walled carbon nanotubes as high efficiency DNA carriers |
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| Xiao Ying Yang, Zun Feng Liu, Jie Mao, Shu Jing Wang, Yan Feng Ma,Yong Sheng Chen,. The preparation of functionalized single walled carbon nanotubes as high efficiency DNA carriers[J]. Chinese Chemical Letters, 2007, 18(12): 1551-1553. DOI: 10.1016/j.cclet.2007.10.006 | |
| Authors: | Xiao Ying Yang Zun Feng Liu Jie Mao Shu Jing Wang Yan Feng Ma Yong Sheng Chen |
| Affiliation: | aSchool of Pharmaceutical Sciences, Tianjin Medical University, Tianjin 300070, China bCenter for Nanoscale Science and Technology and Key Laboratory for Functional Polymer Materials, Institute of Polymer Chemistry, Nankai University, Tianjin 300071, China |
| Abstract: | The positively charged single walled carbon nanotubes (SWNTs+) were prepared by conjugating with CONHC6H12NH3+. The double strand DNA (dsDNA) chains were loaded onto SWNTs+ via the electrostatic interactions. SWNTs+ shows improved loading efficiency (353.5 μg/mg) toward dsDNA compared with that of charged free single walled carbon nanotubes (SWNTs) (82.9 μg/mg). |
| Keywords: | Single walled carbon nanotubes DNA Carrier |
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