Green Synthesis of Spiro[indoline‐3,4′‐pyrazolo[3,4‐b][1,6]naphthyridine]‐2,5′(1′H)‐diones Catalyzed by TsOH in Ionic Liquids |
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| Authors: | Bin‐Bin Feng Rong‐Zhang Jin Mei‐Mei Zhang Xiang‐Shan Wang |
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| Institution: | School of Chemistry and Chemical Engineering, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou, Jiangsu, People's Republic China |
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| Abstract: | A three‐component reaction of isatin, 3‐methyl‐1‐phenyl‐1H‐pyrazol‐5‐amine, and piperidine‐2,4‐dione was treated in ionic liquids catalyzed by TsOH and provided an efficient and green method for the synthesis of spiroindoline‐3,4′‐pyrazolo3, 4‐b]1,6]naphthyridine]‐2,5′(1′H)‐dione derivatives in high yields. |
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