High-performance liquid chromatographic analysis of free palmitic and stearic acids in cerebrospinal fluid |
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| Authors: | I Zamir E Grushka G Cividalli |
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| Affiliation: | Department of Inorganic and Analytical Chemistry, Hebrew University, Jerusalem, Israel. |
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| Abstract: | ![]()
A relatively simple method for extraction of free fatty acids from cerebrospinal fluid with aminopropyl bonded-phase columns, and the estimation of palmitic acid (C16:0) and stearic acid (C18:0) concentrations by high-performance liquid chromatographic analysis is described. The values of C16:0 and C18:0 in patients with non-neurological disorders lie within a narrow range, with a mean (+/- S.D.) of 4.02 +/- 0.33 micrograms/ml for C16:0 and 2.72 +/- 0.39 micrograms/ml for C18:0. |
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