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Protein Staining Agents from Cationic and Neutral Luminescent Iridium(III) Complexes
Authors:Dr Yuyang Zhou  Assistant Prof Junli Jia  Prof Xiaomei Wang  Dr Weiqiang Guo  Prof Zhengying Wu  Prof Nan Xu
Institution:1. Jiangsu Key Laboratory of Environmental Functional Materials, School of Chemistry, Biology and Material Engineering, Suzhou University of Science and Technology, Suzhou, Jiangsu, P. R. China;2. Department of Immunology, Nanjing Medical University, Nanjing, Jiangsu, P. R. China
Abstract:Seven luminescent iridium(III) complexes were prepared to investigate the relationships between chemical structures and properties of protein staining. For the first time, the effect of the main ligand, the π conjugation effect of the ancillary ligand, and the charge effect of organometallic complexes on protein staining has been revealed. Most importantly, this study gives the first experimental evidence of the potential applications of charge‐neutral organometallic complexes in protein staining, which could open an avenue of exploiting novel protein staining agents in the future.
Keywords:iridium  luminescence  neutral complexes  organometallic compounds  protein staining
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