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Total synthesis of two 12-nordrimanes and the pharmacological active sesquiterpene hydroquinone yahazunol |
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| Authors: | Thorsten Laube Karlheinz Seifert |
| Institution: | a Lehrstuhl für Organische Chemie, NW II, Universität Bayreuth, D-95440 Bayreuth, Germany b Institut für Pharmakologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, D-30625 Hannover, Germany |
| Abstract: | The synthesis of two 12-nordrimanes and yahazunol was achieved via 8-oxo-12-nordrimanic acid methyl ester. The cytotoxic activity of yahazunol and seven other sesquiterpene hydroquinones and sesquiterpene quinones has been determined. |
| Keywords: | Terpenes Phenols Quinones |
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