| Synthesis of Hydroxylated Sterols(Ⅱ)--Synthesis of 24-Methylenecholest-4-en-3β,6α-diol |
| |
| 作者姓名： | ZENG Long-mei CUI Jian-guo SU Jing-yu |
| |
| 作者单位： | Department of Chemistry,Zhongshan University,Guangzhou 510275,P.R.China,Department of Chemistry,Zhongshan University,Guangzhou 510275,P.R.China;Department of Chemistry，Guangxi Teachers College，Naning 530001，P.R.China |
| |
| 基金项目： | 中国科学院资助项目，the Natural science foundation of Guangdong Province，the Frontier Science Foundation of Zhongshan University，29932030，970154，，，， |
| |
| 摘 要： | In our study on the soft coral,Alcyonium patagonicum,a new hydroxylated sterol,24-methylenecholest-4-en-3β,6α-diol(1) exhibiting a potent activity to murine leukemia cells(IC50=1 μg/mL) has been isolated1] and synthesized2,3].As a part of our studies on the relationship between the chemical structure and the biological activity of the hydroxylated sterols,the synthesis of 24-methylenecholest-4-en-3β,6α-diol(2) is reported here.
|
| 关 键 词： | Synthesis Reduction 24-Methylenecholest-4-en-3β 6α-diol |
| 收稿时间： | 2000-01-27 |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《高等学校化学研究》浏览原始摘要信息 |
| 点击此处可从《高等学校化学研究》下载免费的PDF全文 |
|
