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A single step synthesis of 6-aminophenanthridines from anilines and 2-chlorobenzonitriles |
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| Authors: | Fabienne Gug Marc Blondel Anne-Sophie Martin |
| Affiliation: | a Laboratoire de Chimie Organique, Université René Descartes, 4 avenue de l'Observatoire, 75006 Paris, France b C.N.R.S., Station Biologique, Cell Cycle Laboratory, place G. Teissier, 29680 Roscoff, Bretagne, France |
| Abstract: | Biologically active 6-aminophenanthridines were prepared in a single step procedure: Metal amides in liquid ammonia promoted the condensation of anilines with 2-chloro-benzonitriles. 6-Aminophenanthridines were isolated in moderate yield. |
| Keywords: | Amidine Prions Phenanthridine Heterocyclisation |
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