A short and efficient general synthesis of luotonin A, B and E |
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| Authors: | Subhash P. Chavan Rasapalli Sivappa |
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| Affiliation: | Division of Organic Chemistry (Technology) National Chemical Laboratory, Pune 411008, India |
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| Abstract: | Highly convergent synthesis of three luotonins (A, B, and E) has been achieved from readily available starting materials. The key step in the synthesis is formation of quinazolinone skeleton by the condensation of 3-(1,3-dioxolan-2-yl-quinoline-2-carbaldehyde and anthranilamide. |
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| Keywords: | Luotonin Synthesis Quinazolinone Mitsunobu Camptothecin |
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