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Synthesis and antitubercular activity of tricyclic analogs of puupehenone
Authors:George A Kraus  Tuan Nguyen  Jesse Hostetter
Affiliation:a Department of Chemistry, Iowa State University, Ames, IA 50011, USA
b Department of Veterinary Pathology, Iowa State University, Ames, IA 50011, USA
Abstract:
Tricyclic analogs 2a and 8 were prepared by four-step routes. The key step was an intermolecular hetero Diels-Alder reaction involving a quinone methide.
Keywords:Tricyclic analogs   Puupehenone   Strongylophora hartmani
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