Tetrabutylammonium cyanide catalyzed diasteroselective cyanosilylation of chiral α-hydroxyketones |
| |
| Authors: | Iñigo Amurrio Joaquín Plumet |
| |
| Institution: | Departamento de Química Orgánica, Facultad de Química, Universidad Complutense, 28040 Madrid, Spain |
| |
| Abstract: | Tetrabutylammonium cyanide has been used as non-metallic catalyst for the diastereoselective cyanosilylation of α-hydroxyketones derived from the chiral pool. This affords α-substituted-α,β-dihydroxynitriles with high levels of asymmetric induction. |
| |
| Keywords: | Tetrabutylammonium cyanide α-Hydroxyketones α β-Dihydroxynitriles |
| 本文献已被 ScienceDirect 等数据库收录！ |
