结构受阻的取代的苯乙烯基吡嗪衍生物作为荧光探针的研究

本工作合成了两种旋转受阻取代的苯乙烯基吡嗪衍生物。详细研究了环境温度、极性和粘度对其光物理及发光行为的影响。结果表明两化合物在基态时可能存在着"平面构象与扭曲构象"间的平衡, 环境的温度、极性和粘度对于化合物存在的构象有很大影响。扭曲构象为较好的发光构象。分子受激后, 平面构象可经旋转松弛到扭曲构象。两化合物的荧光量子产率在室温条件下基本不随溶剂极性变化而变, 仅与溶剂粘度有关, 利用该性质可建议其作为一种有效的粘度荧光探针。

Study on bridged substituted styryl pyrazine derivatives probe fluorophore

Two bridged substituted styryl pyrazine derivatives have been synthesized in this work. The effects of environmental temperature, solvent polarity and viscosity on the photophysics and luminescence behavior of these compounds were studied in detail. Results indicated that a equilibrium between coplanar and twisted conformations existed, and environmental temperature, solvent polarity and viscosity could affect the conformation of these compounds. The twisted conformation was favorable for luminescence, and the excited coplanar molecule could relax to the twisted conformation. Independence between fluorescence quantum yields and solvent polarity at room temperature make it possibly to develop a novel probe for detecting the microviscosity specially.