Syntheses of novel chiral sulfinamido ligands and their applications in diethylzinc additions to aldehydes |
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Authors: | Huang Zhiyan Lai Hongshan Qin Yong |
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Affiliation: | Department of Chemistry of Medicinal Natural Products and Key Laboratory of Drug Targeting, West China School of Pharmacy, Sichuan University, Chengdu 610041, P. R. China. |
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Abstract: | A novel class of sulfinamido alcohol ligands 1-6 was synthesized from (S)-tert-butanesulfinamide. These ligands showed excellent catalytic activities and enantiomeric selectivities in asymmetric additions of diethylzinc to aromatic aldehydes. |
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